\u201cIt\u2019s 25 degrees here,\u201d Sandy Vojta said to me on the phone. \u201cAnd snowing like crazy.\u201d\r\n\r\nSandy Vojta owns Prairie Berry Winery, a lonely outpost in the Black Hills of South Dakota. And she uses grapes from her vineyard in distant Yankton, the only place in the state where grapes will grow. Her wines have fanciful names, such as Phat Hogg Chardonnay, Pink Slip (Chardonnay and Catawba) and Red Ass Rhubarb (a fruit wine).\r\n\r\nReflecting nature itself, wine producers show remarkable resilience and determination in growing grapes where conditions say quite clearly, are you serious?\r\n\r\nCasa Rondena Winery sits in the high desert of Albuquerque, New Mexico. And the lack of rain (10\u201312 inches a year) is only the first challenge. \u201cThe sunlight here is intense,\u201d says owner John Calvin, \u201cand if the foliage of the vines can\u2019t protect them, the grapes will die. The wind can be extreme. And daytime temperatures can get near 100. Our saving grace is that they drop by 30-40 degrees at night.\u201d\r\n\r\nThere\u2019s probably nowhere on Earth less suited for wine production than Hokkaido, northernmost of Japan\u2019s home islands. The winds are fierce. The terrain is mountainous. Winter temperatures hover around zero. There\u2019s up to 40 feet of snow every year. And you actually have to bury the vines in the snow to keep the grapes from dying of frostbite.\r\n\r\nYet, Taichi Yamazaki annually produces 20,000 cases of wine here, including Pinot Noir, Merlot and Chardonnay. He\u2019s a fourth-generation Hokkaido winemaker. But he\u2019s probably the first to play classical music in the vineyards there \u201cTo relieve stress on the grapes,\u201d he says.\r\n\r\nWhen Karim Hwaidak returned to his native Egypt from Tuscany, where his family owns vineyards, he started his own in the Sahara. Desert sand has no nutrients, so the nutrients have to come from compost\u2014thirty tons a year. Drip irrigation requires wells up to 250 yards deep. And if you push the pumping systems too hard, the salinity will rise, which can defoliate vines late in the growing season. Hwaidak coaxes enough fruit from the desert for 16 red wine labels and 14 whites.\r\n\r\nHe\u2019s not alone. Winemakers of the Golan Heights Winery in Israel produce Chardonnays and Merlots on land that\u2019s hot and dusty in the summer and windblown and snowy in the winter.\r\n\r\nThe historical consensus in Europe has been that an elevation of 1,600 feet is the upper limit for worthwhile grape cultivation. But Donald Hess, at Bodega Colome, his property in the farthest north corner of the Argentinean Andes\u2019 Salta province, makes wonderful Malbec and Torront\u00e9s at approximately 9,849 feet\u2014the highest vineyard in the world.\r\n\r\nIn the central Canadian province of Saskatchewan, Cypress Hills Winery is the only commercial vineyard in the three prairie provinces. There are frosts in late May. There\u2019s hail the size of golf balls, says owner Marie Bohnet; in a 2008 hailstorm, all the grapes were lost. There are ferocious \u201cChinook\u201d winds. It can be 40-below in winter, and 100-above in summer. Nonetheless, Cypress Hills sells 3,000 cases a year, all of it to folks who happen to be driving by.\r\n\r\n\u201cNever let fear\u2014or common sense\u2014hold you back,\u201d says Bohnet.\r\n\r\nWords of wisdom from one of a hardy group of winemakers around the world who are, metaphorically speaking, spitting into the wind\u2026and the snow, the altitude and the sun.